Rer1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Rer1^tm1.1Arte
• Name: retention in endoplasmic reticulum sorting receptor 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6392879
• Synonyms: Rer1^fl
• Gene: Rer1 Location: Chr4:155158567-155170839 bp, - strand Genetic Position: Chr4, 86.17 cM
• Alliance: Rer1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253621
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 3 and 4 were flanked by LoxP sites. Positive selection markers were flanked by FRT (NeoR) and F3 (PuroR) sites and inserted into intron 2 and intron 4, respectively. Flp-mediated recombination resulted in the removal of selection markers. (J:253621)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rer1 Mutation: 29 strains or lines available

References

• Original: J:253621 Valkova C, et al., The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels. Sci Rep. 2017 Jan 24;7:41248
• All: 1 reference(s)