Notum^tm1.1Cip
Targeted Allele Detail

Summary

• Symbol: Notum^tm1.1Cip
• Name: notum palmitoleoyl-protein carboxylesterase; targeted mutation 1.1, Christine Perret
• MGI ID: MGI:6363549
• Synonyms: Notum^lox
• Gene: Notum Location: Chr11:120544614-120552001 bp, - strand Genetic Position: Chr11, 84.38 cM
• Alliance: Notum^tm1.1Cip page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279588
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted upstream of exon 2 and downstream of exon 8. Flp-mediated recombination removed the FRT-flanked hygromycin resistance cassette inserted downstream of exon 8. (J:279588)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Notum Mutation: 31 strains or lines available

References

• Original: J:279588 Canal F, et al., Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum. PLoS One. 2016;11(3):e0150997
• All: 5 reference(s)