Mrap^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Mrap^tm1.1Geno
• Name: melanocortin 2 receptor accessory protein; targeted mutation 1.1, Genoway
• MGI ID: MGI:6363201
• Gene: Mrap Location: Chr16:90535095-90546673 bp, + strand Genetic Position: Chr16, 51.9 cM, cytoband C3.3
• Alliance: Mrap^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278935
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the selection cassette and left exon 1 floxed. (J:278935)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrap Mutation: 8 strains or lines available

References

• Original: J:278935 Novoselova TV, et al., MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. FASEB J. 2018 Jun 7;:fj201701274RR
• All: 1 reference(s)