Mir21a^tm1.2Smoc
Targeted Allele Detail

Summary

• Symbol: Mir21a^tm1.2Smoc
• Name: microRNA 21a; targeted mutation 1.2, Shanghai Model Organisms Center
• MGI ID: MGI:6363073
• Synonyms: Mir21a KO
• Gene: Mir21a Location: Chr11:86474893-86474984 bp, - strand Genetic Position: Chr11, 51.82 cM
• Alliance: Mir21a^tm1.2Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:287123
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 1 of the gene was removed via cre-mediated recombination of flanking loxP sites. (J:287123)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir21a Mutation: 10 strains or lines available

References

• Original: J:287123 Bei Y, et al., miR-21 suppression prevents cardiac alterations induced by d-galactose and doxorubicin. J Mol Cell Cardiol. 2018 Jan 9;115:130-141
• All: 7 reference(s)