Amfrtm1.1Blsg
Targeted Allele Detail
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Symbol: |
Amfrtm1.1Blsg |
Name: |
autocrine motility factor receptor; targeted mutation 1.1, Bao-Liang Song |
MGI ID: |
MGI:6358039 |
Synonyms: |
gp78fl |
Gene: |
Amfr Location: Chr8:94698216-94739301 bp, - strand Genetic Position: Chr8, 45.96 cM
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Alliance: |
Amfrtm1.1Blsg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:270119
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S1/SvImJ
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: LoxP sites were inserted into the introns flanking exon 5 and 8, along with a neo cassette (G418 resistance) surrounded by FRT sites as a selectable marker. The neo cassette was removed via FLP-mediated recombination.
(J:270119)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Amfr Mutation: |
42 strains or lines available
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Original: |
J:270119 Liu TF, et al., Ablation of gp78 in liver improves hyperlipidemia and insulin resistance by inhibiting SREBP to decrease lipid biosynthesis. Cell Metab. 2012 Aug 8;16(2):213-25 |
All: |
5 reference(s) |
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