Ecrg4^tm1.1Toko
Targeted Allele Detail

Summary

• Symbol: Ecrg4^tm1.1Toko
• Name: ECRG4 augurin precursor; targeted mutation 1.1, Toru Kondo
• MGI ID: MGI:6355397
• Synonyms: Ecrg4KI
• Gene: Ecrg4 Location: Chr1:43769762-43781724 bp, + strand Genetic Position: Chr1, 23.44 cM, cytoband C1
• Alliance: Ecrg4^tm1.1Toko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:272555
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The first exon was replaced with a loxP-flanked lacZ gene. An FRT-flanked neomyhcin selection cassette was removed via FLP-mediated recombination in the germline. (J:272555)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ecrg4 Mutation: 15 strains or lines available

References

• Original: J:272555 Nakatani Y, et al., Ecrg4 deficiency extends the replicative capacity of neural stem cells in a Foxg1-dependent manner. Development. 2019 Feb 18;146(4):dev168120
• All: 1 reference(s)