Pcdhg^tm1.1Tyag
Targeted Allele Detail

Summary

• Symbol: Pcdhg^tm1.1Tyag
• Name: protocadherin gamma cluster; targeted mutation 1.1, Takeshi Yagi
• MGI ID: MGI:6331322
• Synonyms: gammaLacZ
• Gene: Pcdhg Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:277249
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: This allele has an IRES, a tau-lacZ gene cassette and a loxP site flanked neomycin resistance gene cassette inserted into the 3' UTR of the last shared exon, gammaCR3, of the cluster genes. Subsequent cre-mediated recombination removed the floxed neo cassette, leaving one loxP site in its place. (J:277249)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdhg Mutation: 13 strains or lines available

References

• Original: J:277249 Yokota S, et al., Identification of the cluster control region for the protocadherin-beta genes located beyond the protocadherin-gamma cluster. J Biol Chem. 2011 Sep 9;286(36):31885-95
• All: 3 reference(s)