C1qbp^tm1.2Ypz
Targeted Allele Detail

Summary

• Symbol: C1qbp^tm1.2Ypz
• Name: complement component 1, q subcomponent binding protein; targeted mutation 1.2, Yangping Zhang
• MGI ID: MGI:6306864
• Gene: C1qbp Location: Chr11:70868672-70873852 bp, - strand Genetic Position: Chr11, 43.21 cM
• Alliance: C1qbp^tm1.2Ypz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253035
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 3. (J:253035)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any C1qbp Mutation: 22 strains or lines available

References

• Original: J:253035 Liu Y, et al., p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure. Sci Rep. 2017 Jul 18;7(1):5754
• All: 2 reference(s)