About   Help   FAQ
Tg(RP22-455H18)TG1Rdc
Transgene Detail
Summary
Symbol: Tg(RP22-455H18)TG1Rdc
Name: transgene insertion, Roger D Cox
MGI ID: MGI:6278550
Synonyms: B6-TG1
Transgene: Tg(RP22-455H18)TG1Rdc  Location: unknown  
Alliance: Tg(RP22-455H18)TG1Rdc page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(RP22-455H18)TG1Rdc expresses 1 gene
 
Mutation detailsBAC RP22-455H18, from a 129S6/SvEvTac genomic library, was micro-injected into C57BL/6J one-cell embryos. The BAC contains the complete Nnt gene (plus flanking sequence, possibly including (parts of) flanking genes). Two independent mouse lines were established: B6-TG1 and B6-TG2. In both lines, the transgene complements the NntC57BL/6J null allele. (J:109356)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:109356 Freeman HC, et al., Deletion of Nicotinamide Nucleotide Transhydrogenase: A New Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice. Diabetes. 2006 Jul;55(7):2153-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/30/2025
MGI 6.24
The Jackson Laboratory