Adipoq^tm1Zgwg
Targeted Allele Detail

Summary

• Symbol: Adipoq^tm1Zgwg
• Name: adiponectin, C1Q and collagen domain containing; targeted mutation 1, Zhugang Wang
• MGI ID: MGI:6258860
• Gene: Adipoq Location: Chr16:22965286-22976718 bp, + strand Genetic Position: Chr16, 13.96 cM, cytoband B3-B4
• Alliance: Adipoq^tm1Zgwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:267096
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Gene targeting strategy was designed to replace part of exon 2 and exon 3 of adiponectin gene with full length LacZ gene in frame with remaining upstream ATG and signal peptide sequence of exon 2. (J:267096)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adipoq Mutation: 41 strains or lines available

References

• Original: J:267096 Ren WH, et al., Generation of adiponectin gene knock-out and LacZ gene knock-in mouse model. Progress in Biochemistry and Biophysics. 2006-01-01;33(9):846-853
• All: 4 reference(s)