About   Help   FAQ
Targeted Allele Detail
Symbol: Washc5tm1.2Cbee
Name: WASH complex subunit 5; targeted mutation 1.2, Christian Beetz
MGI ID: MGI:6256428
Synonyms: E430025E21Rikko
Gene: Washc5  Location: Chr15:59203846-59246016 bp, - strand  Genetic Position: Chr15, 25.17 cM
Germline Transmission:  Earliest citation of germline transmission: J:266630
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted 216 bp downstream of exon 12 and a PGK promoter-driven neomycin resistance cassette flanked by frt-sites and preceded by another loxP site were inserted 265 bp upstream of exon 12. The selection cassette was removed via Flp-mediated recombination. Cre-mediated recombination removed exon 12. (J:266630)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Washc5 Mutation:  34 strains or lines available
Original:  J:266630 Jahic A, et al., The spectrum of KIAA0196 variants, and characterization of a murine knockout: implications for the mutational mechanism in hereditary spastic paraplegia type SPG8. Orphanet J Rare Dis. 2015 Nov 16;10:147
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.21
The Jackson Laboratory