Cpeb1^tm1.1Fern
Targeted Allele Detail

Summary

• Symbol: Cpeb1^tm1.1Fern
• Name: cytoplasmic polyadenylation element binding protein 1; targeted mutation 1.1, Mercedes Fernandez
• MGI ID: MGI:6203045
• Gene: Cpeb1 Location: Chr7:80996774-81105207 bp, - strand Genetic Position: Chr7, 45.71 cM
• Alliance: Cpeb1^tm1.1Fern page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265411
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and an FRT flanked inverted neo cassette and loxP site were inserted downstream of exon 4 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:265411)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cpeb1 Mutation: 20 strains or lines available

References

• Original: J:265411 Calderone V, et al., Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease. Gastroenterology. 2016 Apr;150(4):982-97.e30
• All: 2 reference(s)