About   Help   FAQ
Gt(ROSA)26Sortm2.1(CAG-ELOVL1)Geno
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm2.1(CAG-ELOVL1)Geno
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Genoway
MGI ID: MGI:6194785
Synonyms: Rosa26CAG-STOPflox/flox-ELOVL1TG
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077244 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:257393
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Gt(ROSA)26Sortm2.1(CAG-ELOVL1)Geno expresses 1 gene
 
Mutation detailsGenOways quick knock-in approach was used to introduce a loxP-flanked transcriptional STOP cassette and a single copy of the human ELOVL1 cDNA under the control of the CAG promoter into the Rosa26 locus through homologous recombination. Flp-mediated recombination removed a FRT-flanked neomycin cassette. (J:257393)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  510 strains or lines available
References
Original:  J:257393 van de Beek MC, et al., C26:0-Carnitine Is a New Biomarker for X-Linked Adrenoleukodystrophy in Mice and Man. PLoS One. 2016;11(4):e0154597
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/14/2020
MGI 6.14
The Jackson Laboratory