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Targeted Allele Detail
Symbol: Gt(ROSA)26Sortm2.1(CAG-ELOVL1)Geno
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Genoway
MGI ID: MGI:6194785
Synonyms: Rosa26CAG-STOPflox/flox-ELOVL1TG
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077244 bp, - strand  Genetic Position: Chr6, 52.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:257393
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
Gt(ROSA)26Sortm2.1(CAG-ELOVL1)Geno expresses 1 gene
Mutation detailsGenOways quick knock-in approach was used to introduce a loxP-flanked transcriptional STOP cassette and a single copy of the human ELOVL1 cDNA under the control of the CAG promoter into the Rosa26 locus through homologous recombination. Flp-mediated recombination removed a FRT-flanked neomycin cassette. (J:257393)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  510 strains or lines available
Original:  J:257393 van de Beek MC, et al., C26:0-Carnitine Is a New Biomarker for X-Linked Adrenoleukodystrophy in Mice and Man. PLoS One. 2016;11(4):e0154597
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory