Pnldc1^em1Pdz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pnldc1^em1Pdz
• Name: poly(A)-specific ribonuclease (PARN)-like domain containing 1; endonuclease-mediated mutation 1, Phillip Zamore
• MGI ID: MGI:6161374
• Synonyms: Pnldc1^-
• Gene: Pnldc1 Location: Chr17:13107616-13129117 bp, - strand Genetic Position: Chr17, 8.71 cM
• Alliance: Pnldc1^em1Pdz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-mediated 526 bp deletion of exons 1 and 2 (chr17:12,909,434-12,909,959). The deletion generates a null allele. (J:266329)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pnldc1 Mutation: 28 strains or lines available

References

• Original: J:266329 Gainetdinov I, et al., A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals. Mol Cell. 2018 Sep 6;71(5):775-790.e5
• All: 2 reference(s)