Dpysl2^tm2Gosh
Targeted Allele Detail

Summary

• Symbol: Dpysl2^tm2Gosh
• Name: dihydropyrimidinase-like 2; targeted mutation 2, Yoshio Goshima
• MGI ID: MGI:6153122
• Synonyms: crmp2^-
• Gene: Dpysl2 Location: Chr14:67040313-67148410 bp, - strand Genetic Position: Chr14, 34.6 cM
• Alliance: Dpysl2^tm2Gosh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260670
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP-flanked neomycin selection cassette replaced a genomic fragment of the gene which includes exons 2, 3 and 4. Immunoblot analysis of mouse brain lysates indicated that no detectable encoded protein was present in homozygous mice. (J:260670)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dpysl2 Mutation: 36 strains or lines available

References

• Original: J:260670 Makihara H, et al., CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development. Genes Cells. 2016 Sep;21(9):994-1005
• All: 5 reference(s)