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Daam1tm1.1Tpy
Targeted Allele Detail
Nomenclature
Symbol: Daam1tm1.1Tpy
Name: dishevelled associated activator of morphogenesis 1; targeted mutation 1.1, Terry Yamaguchi
MGI ID: MGI:6149780
Synonyms: Daam1floxed
Gene: Daam1  Location: Chr12:71831078-71992333 bp, + strand  Genetic Position: Chr12, 30.06 cM, cytoband C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:228507
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted into SalI and BglII sites within the introns 5 and 6, respectively. An FRT site flanked neomycin selection cassette was inserted into intron 6 and was subsequently removed via flp-mediated recombination, leavuing a conditional-ready allele with exon 6 floxed. (J:228507)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Daam1 Mutation:  21 strains or lines available
References
Original:  J:228507 Ajima R, et al., DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly. Dev Biol. 2015 Dec 1;408(1):126-39
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory