Dock8^em2Seis
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dock8^em2Seis
• Name: dedicator of cytokinesis 8; endonuclease-mediated mutation 2, Stephanie C Eisenbarth
• MGI ID: MGI:6149570
• Gene: Dock8 Location: Chr19:24976898-25179796 bp, + strand Genetic Position: Chr19, 19.91 cM
• Alliance: Dock8^em2Seis page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated mutation introduced loxP sites flanking exons 10-14. (J:259009)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock8 Mutation: 103 strains or lines available

References

• Original: J:259009 Krishnaswamy JK, et al., Migratory CD11b(+) conventional dendritic cells induce T follicular helper cell-dependent antibody responses. Sci Immunol. 2017 Dec 1;2(18)
• All: 3 reference(s)