Adamts18tm1Wzha
Targeted Allele Detail
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Symbol: |
Adamts18tm1Wzha |
Name: |
ADAM metallopeptidase with thrombospondin type 1 motif 18; targeted mutation 1, Wei Zhang |
MGI ID: |
MGI:6148034 |
Gene: |
Adamts18 Location: Chr8:114423758-114575370 bp, - strand Genetic Position: Chr8, 59.65 cM
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Alliance: |
Adamts18tm1Wzha page
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Germline Transmission: |
Earliest citation of germline transmission:
J:258487
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: A loxP site and FRT flanked pgk-neo cassette were inserted upstream of exon 5 and a loxP site was inserted downstream of exon 6 via homologous recombination.
(J:258487)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Adamts18 Mutation: |
65 strains or lines available
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Original: |
J:258487 Lu T, et al., Adamts18 deficiency promotes colon carcinogenesis by enhancing beta-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer. Oncotarget. 2017 Mar 21;8(12):18979-18990 |
All: |
1 reference(s) |
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