Pgap6^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Pgap6^tm1Osb
• Name: post-glycosylphosphatidylinositol attachment to proteins 6; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6147693
• Synonyms: Pgap6^-, Pgap6^tm1Maik
• Gene: Pgap6 Location: Chr17:26332290-26342228 bp, + strand Genetic Position: Chr17, 13.06 cM, cytoband B1
• Alliance: Pgap6^tm1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258200
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

Allele Type: Targeted (Null/knockout) Mutation: Insertion An exon-trap construct from EUCOMM was used to disrupt the gene. (J:258200)

Generation of the Pgap6^tm1Osb allele

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgap6 Mutation: 36 strains or lines available

References

• Original: J:258200 Lee GH, et al., A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO. J Cell Biol. 2016 Dec 5;215(5):705-718
• All: 1 reference(s)