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Kcnj6em1.1Ktaka
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Kcnj6em1.1Ktaka
Name: potassium inwardly-rectifying channel, subfamily J, member 6; endonuclease-mediated mutation 1.1, Kazuo Takahama
MGI ID: MGI:6144032
Synonyms: Girk2floxed
Gene: Kcnj6  Location: Chr16:94549495-94798560 bp, - strand  Genetic Position: Chr16, 55.44 cM
Mutation
origin
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready)
Mutation:    Insertion
 
Mutation detailsCRISPR/Cas9 technology inserted loxP sites flanking exon 4a and a FRT-flanked neomycin selection cassette downstream of the floxed exon. Flp-mediated recombination deleted the neomycin cassette. (J:257982)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnj6 Mutation:  16 strains or lines available
Notes
ES Cells: 6NK7
References
Original:  J:257982 Honda I, et al., Deletion of GIRK2 subunit containing GIRK channels of neurons expressing dopamine transporter decrease immobility time on forced swimming in mice. Neurosci Lett. 2018 Feb 5;665:140-146
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory