Tg(Myh6-Mir133a-1)1Gwd
Transgene Detail

Summary

• Symbol: Tg(Myh6-Mir133a-1)1Gwd
• Name: transgene insertion 1, Gerald W Dorn
• MGI ID: MGI:6140103
• Synonyms: alphaMHC-miR-133a
• Transgene: Tg(Myh6-Mir133a-1)1Gwd Location: unknown
• Alliance: Tg(Myh6-Mir133a-1)1Gwd page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Mir133a-1)1Gwd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir133a-1 (MGI:2676818)

• Mutation details: A rat cardiac alpha myosin heavy chain promoter was used to drive expression the mouse miR-133a-1 gene. (J:170069)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:170069 Matkovich SJ, et al., MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res. 2010 Jan 8;106(1):166-75
• All: 4 reference(s)