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Pgrmc2tm1.1Jjp
Targeted Allele Detail
Nomenclature
Symbol: Pgrmc2tm1.1Jjp
Name: progesterone receptor membrane component 2; targeted mutation 1.1, John J Peluso
MGI ID: MGI:6118911
Synonyms: Pgrmc2fl
Gene: Pgrmc2  Location: Chr3:41066326-41083046 bp, - strand  Genetic Position: Chr3, 19.66 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:247103
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129 x C57BL/6J
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exons 2 and 3 were floxed. Flp-mediated recombination removed the selection cassette. (J:247103)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pgrmc2 Mutation:  4 strains or lines available
References
Original:  J:247103 Clark NC, et al., Conditional Ablation of Progesterone Receptor Membrane Component 2 Causes Female Premature Reproductive Senescence. Endocrinology. 2017 Mar 01;158(3):640-651
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory