Piezo1tm2Apat
Targeted Allele Detail
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Symbol: |
Piezo1tm2Apat |
Name: |
piezo-type mechanosensitive ion channel component 1; targeted mutation 2, Ardem Patapoutian |
MGI ID: |
MGI:5911416 |
Synonyms: |
Piezo1LacZ |
Gene: |
Piezo1 Location: Chr8:123208437-123278068 bp, - strand Genetic Position: Chr8, 71.31 cM
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Alliance: |
Piezo1tm2Apat page
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Germline Transmission: |
Earliest citation of germline transmission:
J:229436
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Conditional ready, Reporter) |
Mutation: |
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Insertion
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Mutation details: The L1L2_Bact_P cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. The FRT-lacZ-loxP-neo-FRT-loxP cassette is introduced into intron 19 followed by a loxP site placed in intron 23.
(J:229436)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Piezo1 Mutation: |
87 strains or lines available
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Original: |
J:229436 Cahalan SM, et al., Piezo1 links mechanical forces to red blood cell volume. Elife. 2015;4 |
All: |
2 reference(s) |
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