Tg(CD3E,CD3D,CD3G)1Csk
Transgene Detail

Summary

• Symbol: Tg(CD3E,CD3D,CD3G)1Csk
• Name: transgene insertion 1, Chugai Pharmaceutical Co, Ltd
• MGI ID: MGI:5910029
• Synonyms: hCD3 EDG Tg
• Transgene: Tg(CD3E,CD3D,CD3G)1Csk Location: unknown
• Alliance: Tg(CD3E,CD3D,CD3G)1Csk page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD3E,CD3D,CD3G)1Csk expresses 3 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD3D (915)

  Cd3d	(MGI:88331)

  human

  CD3E (916)

  Cd3e	(MGI:88332)

  human

  CD3G (917)

  Cd3g	(MGI:88333)

• The transgene contains three human genes. Line 1 was generated. (J:243702)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Trangene insertion occured in ES cells containing Del(9Cd3g-Cd3e)1Csk.

References

• Original: J:243702 Ueda O, et al., Entire CD3epsilon, delta, and gamma humanized mouse to evaluate human CD3-mediated therapeutics. Sci Rep. 2017 Apr 03;7:45839
• All: 1 reference(s)