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Del(9Cd3g-Cd3e)1Csk
Targeted Allele Detail
Summary
Symbol: Del(9Cd3g-Cd3e)1Csk
Name: deletion, Chr 9, Chugai Pharmaceutical Co, Ltd; deletion, Chr 9, Chugai Pharmaceutical Co, Ltd 1
MGI ID: MGI:5910028
Synonyms: Del1Csk, mCd3 edg-
Gene: Del(9Cd3g-Cd3e)1Csk  Location: unknown  Genetic Position: Chr9, Syntenic
Mutation
origin
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion, Intragenic deletion
  Del(9Cd3g-Cd3e)1Csk involves 3 genes/genome features (Cd3g, Cd3d, Cd3e) View all
 
Mutation detailsA neomycin resistance cassette with a 5' loxP site was inserted upstream of Cd3e. A Rox-flanked hygromycin resistance cassette with a 5' loxP site was inserted downstream of Cd3g. Cre- and Dre-mediated recombination removed Cd3e, Cd3d and Cd3g along with both selection cassettes. (J:243702)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(9Cd3g-Cd3e)1Csk Mutation:  0 strains or lines available
References
Original:  J:243702 Ueda O, et al., Entire CD3epsilon, delta, and gamma humanized mouse to evaluate human CD3-mediated therapeutics. Sci Rep. 2017 Apr 03;7:45839
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory