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Zdhhc16tm1Goff
Targeted Allele Detail
Nomenclature
Symbol: Zdhhc16tm1Goff
Name: zinc finger, DHHC domain containing 16; targeted mutation 1, Stephen P Goff
MGI ID: MGI:5907020
Gene: Zdhhc16  Location: Chr19:41933480-41944104 bp, + strand  Genetic Position: Chr19, 35.48 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:228307
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 were replaced with a pgk-neo cassette via homologous recombination. Northern blot analysis of liver RNA from homozygous pups confirmed the absence of mRNA expression. (J:228307)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zdhhc16 Mutation:  14 strains or lines available
References
Original:  J:228307 Zhou T, et al., Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15666-71
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory