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Syde1tm1.1Hwch
Targeted Allele Detail
Nomenclature
Symbol: Syde1tm1.1Hwch
Name: synapse defective 1, Rho GTPase, homolog 1 (C. elegans); targeted mutation 1.1, Hungwen Chen
MGI ID: MGI:5905625
Gene: Syde1  Location: Chr10:78420337-78427798 bp, - strand  Genetic Position: Chr10, 39.72 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:241798
Parent Cell Line:  C2J (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J/J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exons 2 through 4 and the selection cassette. (J:241798)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 39 assay results
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syde1 Mutation:  16 strains or lines available
References
Original:  J:241798 Lo HF, et al., Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion. J Pathol. 2017 Feb;241(3):324-336
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory