Mir10atm1Wtsi
Targeted Allele Detail
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Symbol: |
Mir10atm1Wtsi |
Name: |
microRNA 10a; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5898049 |
Synonyms: |
Mir10atm1(mirKO)Wtsi |
Gene: |
Mir10a Location: Chr11:96207991-96208100 bp, + strand Genetic Position: Chr11, 59.83 cM
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Mutant Cell Lines: |
mirKO_ES_PuDtk_35D9, mirKO_ES_PuDtk_35D10, mirKO_ES_PuDtk_35D11, mirKO_ES_PuDtk_35D12 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
Sanger miRNA knockouts
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The insertion of the PGK_EM7_PuDtk_bGHpA cassette created a deletion starting at position 96133225 and ending at position 96133378 of Chromosome 11 (Genome Build 38). This deletion eliminates the DNA sequence for this microRNA. The cassette is composed of a loxP site followed by an F3 site followed by a PGK-puromycin-delta-tk cassette, a loxP site and an FRT site.
(J:174268)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mir10a Mutation: |
2 strains or lines available
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Original: |
J:174268 Prosser HM, et al., A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug 7;29(9):840-5 |
All: |
1 reference(s) |
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