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Targeted Allele Detail
Symbol: Fgf3tm1Lwd
Name: fibroblast growth factor 3; targeted mutation 1, Mark Lewandoski
MGI ID: MGI:5888884
Synonyms: Fgfdelta
Gene: Fgf3  Location: Chr7:144392349-144397085 bp, + strand  Genetic Position: Chr7, 88.85 cM
Germline Transmission:  Earliest citation of germline transmission: J:229949
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA hygromycin B cassette is used to replace the coding region, starting 261 bp upstraim of the start codon and ending downstream of the stop codon (5810 bp total). (J:229949)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf3 Mutation:  16 strains or lines available
This mutation was generated by re-targeting v6.4 ES cells in which Fgf4 had been targeted to create Fgf4tm1.1Lwd. Both mutations were determined to be in cis on the 129 chromosome and are tightly linked. (J:229949)
Original:  J:229949 Anderson MJ, et al., Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development. Genesis. 2016 Feb;54(2):91-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
The Jackson Laboratory