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Pbrm1tm1Zhwa
Targeted Allele Detail
Summary
Symbol: Pbrm1tm1Zhwa
Name: polybromo 1; targeted mutation 1, Zhong Wang
MGI ID: MGI:5810066
Synonyms: BAF180fl, Pbrm1tm1.1Zhwa
Gene: Pbrm1  Location: Chr14:30741095-30843549 bp, + strand  Genetic Position: Chr14, 19.09 cM, cytoband B
Alliance: Pbrm1tm1Zhwa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:236906
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA targeting vector is designed to insert a single loxP site upstream of exon 11, and an FRT-flanked betageo cassette, followed by a loxP site, downstream of exon 11. (J:236906)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pbrm1 Mutation:  90 strains or lines available
References
Original:  J:236906 Wurster AL, et al., IL-10 transcription is negatively regulated by BAF180, a component of the SWI/SNF chromatin remodeling enzyme. BMC Immunol. 2012 Feb 15;13:9
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory