Kif17^tm1.2Wbae
Targeted Allele Detail

Summary

• Symbol: Kif17^tm1.2Wbae
• Name: kinesin family member 17; targeted mutation 1.2, Wolfgang Baehr
• MGI ID: MGI:5804008
• Gene: Kif17 Location: Chr4:137989562-138029284 bp, + strand Genetic Position: Chr4, 70.07 cM, cytoband D3
• Alliance: Kif17^tm1.2Wbae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227137
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 4. Immunohistochemistry confirmed the absence of protein expression in photoreceptors. (J:227137)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif17 Mutation: 36 strains or lines available

References

• Original: J:227137 Jiang L, et al., Kinesin family 17 (osmotic avoidance abnormal-3) is dispensable for photoreceptor morphology and function. FASEB J. 2015 Dec;29(12):4866-80
• All: 1 reference(s)