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Agbl2em1Zfa
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Agbl2em1Zfa
Name: ATP/GTP binding protein-like 2; endonuclease-mediated mutation 1, Zusen Fan
MGI ID: MGI:5787967
Gene: Agbl2  Location: Chr2:90782587-90834272 bp, + strand  Genetic Position: Chr2, 50.37 cM
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/Cas9 mediated mutagenesis created a 2 bp deletion in exon 7. (J:231311)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Agbl2 Mutation:  46 strains or lines available
References
Original:  J:231311 Xia P, et al., Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity. Nat Immunol. 2016 Apr;17(4):369-78
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory