Sorbs2^tm2Gfng
Targeted Allele Detail

Summary

• Symbol: Sorbs2^tm2Gfng
• Name: sorbin and SH3 domain containing 2; targeted mutation 2, Guoping Feng
• MGI ID: MGI:5775608
• Synonyms: nArgBP2^-
• Gene: Sorbs2 Location: Chr8:45960825-46280943 bp, + strand Genetic Position: Chr8, 25.44 cM
• Alliance: Sorbs2^tm2Gfng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The targeting vector was designed to delete the neuronal-specific exon (NSE; exon 16) and replaced with a neomycin resistance cassette. The investigator reports that brain tissue from homozygous mice have no detectable protein expression of the nArgBP2 isoform. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sorbs2 Mutation: 79 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)