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Targeted Allele Detail
Symbol: Chn1tm3.1Ito
Name: chimerin 1; targeted mutation 3.1, Shigeyoshi Itohara
MGI ID: MGI:5754365
Synonyms: Chn1alpha1flox
Gene: Chn1  Location: Chr2:73441004-73605690 bp, - strand  Genetic Position: Chr2, 43.78 cM
Alliance: Chn1tm3.1Ito page
Germline Transmission:  Earliest citation of germline transmission: J:229380
Parent Cell Line:  MS12 (ES Cell)
Strain of Origin:  C57BL/6NSlc
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
Mutation detailsAn FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upsteam of exon 7. An additional loxP site was inserted into the untranslated region of exon 7. Flp-mediated recombination removed the selection cassette and left the untranslated region in exon 7 floxed. (J:229380)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chn1 Mutation:  38 strains or lines available
Original:  J:229380 Iwata R, et al., RacGAP alpha2-chimaerin function in development adjusts cognitive ability in adulthood. Cell Rep. 2014 Sep 11;8(5):1257-64
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory