Nell2^tm1.2Matl
Targeted Allele Detail

Summary

• Symbol: Nell2^tm1.2Matl
• Name: NEL-like 2; targeted mutation 1.2, Marc Tessier-Lavigne
• MGI ID: MGI:5707731
• Gene: Nell2 Location: Chr15:95117321-95426677 bp, - strand Genetic Position: Chr15, 49.39 cM, cytoband F1
• Alliance: Nell2^tm1.2Matl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227045
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Frt-neo-frt cassette followed with loxP site were inserted into intron 3 and a second loxP site in intron 1. Recombinase acitivity removed the neo cassette and exons 2 to 3. (J:227045)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nell2 Mutation: 46 strains or lines available

References

• Original: J:227045 Jaworski A, et al., Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2. Science. 2015 Nov 20;350(6263):961-5
• All: 2 reference(s)