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Lonp1tm1Otin
Targeted Allele Detail
Nomenclature
Symbol: Lonp1tm1Otin
Name: lon peptidase 1, mitochondrial; targeted mutation 1, Carlos Lopez-Otin
MGI ID: MGI:5707160
Gene: Lonp1  Location: Chr17:56614297-56626887 bp, - strand  Genetic Position: Chr17, 29.42 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:221992
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    A beta-geo cassette replaced exons 2-4. (J:221992)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lonp1 Mutation:  28 strains or lines available
References
Original:  J:221992 Quiros PM, et al., ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity. Cell Rep. 2014 Jul 24;8(2):542-56
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory