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Mir92-1tm1.1Sdim
Targeted Allele Detail
Nomenclature
Symbol: Mir92-1tm1.1Sdim
Name: microRNA 92-1; targeted mutation 1.1, Stefanie Dimmeler
MGI ID: MGI:5706715
Gene: Mir92-1  Location: Chr14:115281859-115281938 bp, + strand  Genetic Position: Chr14, 59.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:218943
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe microRNA sequence was flanked by loxP sites and a neomycin gene flanked by FRT sites. Cre-mediated recombination removed the microRNA sequence. (J:218943)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir92-1 Mutation:  4 strains or lines available
References
Original:  J:218943 Penzkofer D, et al., Phenotypic characterization of miR-92a-/- mice reveals an important function of miR-92a in skeletal development. PLoS One. 2014;9(6):e101153
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory