Phenotypes associated with this allele

• Allele Symbol: Mir92-1^tm1.1Sdim
• Allele Name: targeted mutation 1.1, Stefanie Dimmeler
• Allele ID: MGI:5706715
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mir92-1^tm1.1Sdim/Mir92-1^tm1.1Sdim	involves: 129S2/SvPas	MGI:5706727

Genotype
MGI:5706727

hm1

• Allelic Composition: Mir92-1^tm1.1Sdim/Mir92-1^tm1.1Sdim
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:218943 )

• loss occurs during the first two weeks after birth

• however, normal numbers of mice are present at E9.5 and E15.5

growth/size/body

decreased body size ( J:218943 )

decreased body weight ( J:218943 )

decreased body length ( J:218943 )

decreased fetal weight ( J:218943 )

skeleton

skeleton phenotype ( J:218943 )

N • bone density is normal

small cranium ( J:218943 )

brachyphalangia ( J:218943 )

• decreased length of the fifth mesophalanx to fifth metacarpal bone of the forelimbs

short tibia ( J:218943 )

cardiovascular system

cardiovascular system phenotype ( J:218943 )

N • mice exhibit normal heart morphology and capillary density in muscle tissue

hematopoietic system

hematopoietic system phenotype ( J:218943 )

N

craniofacial

small cranium ( J:218943 )

limbs/digits/tail

brachyphalangia ( J:218943 )

• decreased length of the fifth mesophalanx to fifth metacarpal bone of the forelimbs

short tibia ( J:218943 )