Cd36^tm2.1Mfe
Targeted Allele Detail

Summary

• Symbol: Cd36^tm2.1Mfe
• Name: CD36 molecule; targeted mutation 2.1, Maria Febbraio
• MGI ID: MGI:5703985
• Synonyms: Cd36^Fl
• Gene: Cd36 Location: Chr5:17986688-18093799 bp, - strand Genetic Position: Chr5, 8.11 cM
• Alliance: Cd36^tm2.1Mfe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225392
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exon 2 and 3 floxed. (J:225392)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd36 Mutation: 32 strains or lines available

References

• Original: J:225392 Nagendran J, et al., Cardiomyocyte-specific ablation of CD36 improves post-ischemic functional recovery. J Mol Cell Cardiol. 2013 Oct;63:180-8
• All: 12 reference(s)