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Socs2tm1Vem
Targeted Allele Detail
Nomenclature
Symbol: Socs2tm1Vem
Name: suppressor of cytokine signaling 2; targeted mutation 1, Vicky E MacRae
MGI ID: MGI:5695065
Gene: Socs2  Location: Chr10:95385362-95417180 bp, - strand  Genetic Position: Chr10, 49.35 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:225936
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    An IRES beta-geo cassette was inserted into exon 2 downstream of the coding sequence. (J:225936)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Socs2 Mutation:  10 strains or lines available
References
Original:  J:225936 Macrae VE, et al., Increased bone mass, altered trabecular architecture and modified growth plate organization in the growing skeleton of SOCS2 deficient mice. J Cell Physiol. 2009 Feb;218(2):276-84
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/10/2019
MGI 6.14
The Jackson Laboratory