Malt1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Malt1^m2Btlr
• Name: MALT1 paracaspase; mutation 2, Bruce Beutler
• MGI ID: MGI:5688602
• Synonyms: yellowstone
• Gene: Malt1 Location: Chr18:65564010-65611959 bp, + strand Genetic Position: Chr18, 38.56 cM
• Alliance: Malt1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transition at base pair 65,458,200 (v38) on chromosome 18, or base pair 27,332 in the NC_000071 GenBank genomic region. The mutation corresponds to residue 1,216 in the mRNA sequence NM_172833 within exon 9 of 16 total exons. The mutation results in an asparagine (N) to lysine (K) substitution at position 347 (N347K) in the protein. (J:224671)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Malt1 Mutation: 33 strains or lines available

References

• Original: J:224671 Wang K-W, et al., Mutagenetix entry for yellowstone. MGI Direct Data Submission. 2015
• All: 1 reference(s)