Chrna4^tm1.1Rmdr
Targeted Allele Detail

Summary

• Symbol: Chrna4^tm1.1Rmdr
• Name: cholinergic receptor, nicotinic, alpha polypeptide 4; targeted mutation 1.1, Ryan M Drenan
• MGI ID: MGI:5659919
• Gene: Chrna4 Location: Chr2:180664104-180685339 bp, - strand Genetic Position: Chr2, 103.54 cM
• Alliance: Chrna4^tm1.1Rmdr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215388
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: GFP was inserted in frame in exon 5 in the M3-M4 loop and a floxed neo cassette was inserted downstream of exon 5 via homologous recombination. Cre mediated recombination removed the neo cassette. (J:215388)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chrna4 Mutation: 42 strains or lines available

References

• Original: J:215388 Shih PY, et al., Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula. J Neurosci. 2014 Jul 16;34(29):9789-802
• All: 2 reference(s)