About   Help   FAQ
Tg(Myh6-Htr2b)1Lum
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-Htr2b)1Lum
Name: transgene insertion 1, Luc Maroteaux
MGI ID: MGI:5645783
Transgene: Tg(Myh6-Htr2b)1Lum  Location: unknown  
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-Htr2b)1Lum expresses 1 gene
 
Mutation detailsThe mouse alpha-myosin heavy chain (MHC) promoter drives the expression of mouse Htr2b cDNA in the heart. Immunoblot analysis showed that the HTR2B protein level was increased in heart lysate of transgenic compared with nontransgenic (NTG) mice. (J:128784)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:128784 Nebigil CG, et al., Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy. Circulation. 2003 Jul 1;107(25):3223-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/07/2017
MGI 6.11
The Jackson Laboratory