Mir7-1^tm1.1Stf
Targeted Allele Detail

Summary

• Symbol: Mir7-1^tm1.1Stf
• Name: microRNA 7-1; targeted mutation 1.1, Markus Stoffel
• MGI ID: MGI:5638150
• Synonyms: Mir7a1^fl
• Gene: Mir7-1 Location: Chr13:58540593-58540700 bp, - strand Genetic Position: Chr13, 31.04 cM
• Alliance: Mir7-1^tm1.1Stf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212929
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT flanked neo cassette and a loxP site were inserted 252 bp upstream of the precursor sequence and a loxP site was inserted 22 bp downstream of the precursor sequence. Flp mediated recombination removed the neo cassette. (J:212929)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir7-1 Mutation: 3 strains or lines available

References

• Original: J:212929 Latreille M, et al., MicroRNA-7a regulates pancreatic beta cell function. J Clin Invest. 2014 Jun 2;124(6):2722-35
• All: 5 reference(s)