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Mir7-1 Gene Detail
Summary
  • Symbol
    Mir7-1
  • Name
    microRNA 7-1
  • Synonyms
    mir 7-1, miR-7a1, Mir7a1, Mirn7-1, mmu-mir-7-1, mmu-mir-7a-1, mmu-miR-7a1
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619436
    NCBI Gene: 723902
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:58540593-58540700 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 31.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619436
miRNA gene Chr13:58540593-58540700 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008074
miRNA gene Chr13:58032943-58033050 (-)
A/J MGP_AJ_G0008063
miRNA gene Chr13:55878577-55878684 (-)
AKR/J MGP_AKRJ_G0008041
miRNA gene Chr13:57540825-57540932 (-)
BALB/cJ MGP_BALBcJ_G0008044
miRNA gene Chr13:56138117-56138224 (-)
C3H/HeJ MGP_C3HHeJ_G0007988
miRNA gene Chr13:57349656-57349763 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008228
miRNA gene Chr13:59815407-59815514 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007337
miRNA gene Chr13:53771662-53771769 (-)
CAST/EiJ MGP_CASTEiJ_G0007874
miRNA gene Chr13:57482559-57482666 (-)
CBA/J MGP_CBAJ_G0007958
miRNA gene Chr13:62064651-62064758 (-)
DBA/2J MGP_DBA2J_G0007992
miRNA gene Chr13:55429705-55429812 (-)
FVB/NJ MGP_FVBNJ_G0008013
miRNA gene Chr13:54906694-54906801 (-)
LP/J MGP_LPJ_G0008074
miRNA gene Chr13:58302587-58302694 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0007985
miRNA gene Chr13:61424316-61424423 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008228
miRNA gene Chr13:57145737-57145844 (-)
PWK/PhJ MGP_PWKPhJ_G0007791
miRNA gene Chr13:55437032-55437139 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007688
miRNA gene Chr13:56055449-56055556 (-)
WSB/EiJ MGP_WSBEiJ_G0007943
miRNA gene Chr13:57579287-57579394 (-)



Homology
more
  • Human Ortholog
    MIR7-1, microRNA 7-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR7-1, microRNA 7-1
  • Synonyms
    hsa-mir-7-1, mir-7-1, MIRN7-1
  • Links
    NCBI Gene ID: 407043

  • Chr Location
    chr9:83969748-83969857 (-)  GRCh38

  • Human Ortholog
    MIR7-2, microRNA 7-2
  • Synonyms
    hsa-mir-7-2, mir-7-2, MIRN7-2
  • Links
    NCBI Gene ID: 407044

  • Chr Location
    chr15:88611825-88611934 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Mir7-1
  • Find Mice (IMSR)
Mice homozygous for a knock-out allele of Mir7-1 and Mir7b are born in expected Mendelian frequency and are grossly normal.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723902 NCBI Gene Model | MGI Sequence Detail 108 C57BL/6J ±  kb
transcript NR_029825 RefSeq | MGI Sequence Detail 108 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 14
    Primer pair 8
    Other 6
Other Database
Links
less
miRBase MI0000728
References
more
  • Summaries
    All 50
    Developmental Gene Expression 18
    Gene Ontology 10
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:333937 LaPierre MP, et al., MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis. Nat Commun. 2022 Sep 29;13(1):5733

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory