Nrxn2^tm4Sud
Targeted Allele Detail

Summary

• Symbol: Nrxn2^tm4Sud
• Name: neurexin II; targeted mutation 4, Thomas C Sudhof
• MGI ID: MGI:5605009
• Synonyms: Nrxn2^flox
• Gene: Nrxn2 Location: Chr19:6468786-6583247 bp, + strand Genetic Position: Chr19, 4.65 cM
• Alliance: Nrxn2^tm4Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 20 followed by a frt-flanked neomycin resistance cassette, and a second loxP site downstream of exon 20. Also, splice site 4, upstream of exon 20, was mutated to a canonical splice acceptor sequence. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nrxn2 Mutation: 87 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 4 reference(s)