Bsg^tm1.1Znc
Targeted Allele Detail

Summary

• Symbol: Bsg^tm1.1Znc
• Name: basigin; targeted mutation 1.1, Zhi-Nan Chen
• MGI ID: MGI:5587937
• Synonyms: Bsg^fl
• Gene: Bsg Location: Chr10:79540325-79547803 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Bsg^tm1.1Znc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207886
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the selection cassette and left exons 2 through 7 floxed. (J:207886)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bsg Mutation: 15 strains or lines available

References

• Original: J:207886 Yao H, et al., Important functional roles of basigin in thymocyte development and T cell activation. Int J Biol Sci. 2013;10(1):43-52
• All: 6 reference(s)