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Foxj1tm1.1(cre/ERT2/GFP)Htg
Targeted Allele Detail
Nomenclature
Symbol: Foxj1tm1.1(cre/ERT2/GFP)Htg
Name: forkhead box J1; targeted mutation 1.1, H Troy Gashghaei
MGI ID: MGI:5585638
Synonyms: Foxj1CreERT2::GFP, Foxj1tmHtg, GCE mice
Gene: Foxj1  Location: Chr11:116221530-116226225 bp, - strand  Genetic Position: Chr11, 81.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213359
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA cassette composed of a GFP, cre, an ERT2 and finally an FRT flanked neomycin selection cassette was inserted in exon 2 before the translation start site. The selection cassette was subsequently removed by flp recombinase expression. (J:213359)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Foxj1     Summary of all recombinase alleles driven by Foxj1. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxj1 Mutation:  9 strains or lines available
References
Original:  J:213359 Muthusamy N, et al., A knock-in Foxj1(CreERT2::GFP) mouse for recombination in epithelial cells with motile cilia. Genesis. 2014 Apr;52(4):350-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory