Foxj1^{tm1.1(cre/ERT2/GFP)Htg}
Targeted Allele Detail

Summary

• Symbol: Foxj1^{tm1.1(cre/ERT2/GFP)Htg}
• Name: forkhead box J1; targeted mutation 1.1, H Troy Gashghaei
• MGI ID: MGI:5585638
• Synonyms: Foxj1^CreERT2::GFP, Foxj1^tmHtg, GCE mice
• Gene: Foxj1 Location: Chr11:116221530-116226225 bp, - strand Genetic Position: Chr11, 81.16 cM
• Alliance: Foxj1^{tm1.1(cre/ERT2/GFP)Htg} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213359
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Foxj1^{tm1.1(cre/ERT2/GFP)Htg} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Foxj1 (MGI:1347474)

• Mutation details: A cassette composed of a GFP, cre, an ERT2 and finally an FRT flanked neomycin selection cassette was inserted in exon 2 before the translation start site. The selection cassette was subsequently removed by flp recombinase expression. (J:213359)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxj1 (mouse) Summary of all recombinase alleles driven by Foxj1. Comparative matrix view of recombinase activities Alliance mouse Foxj1 gene page

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxj1 Mutation: 20 strains or lines available

References

• Original: J:213359 Muthusamy N, et al., A knock-in Foxj1(CreERT2::GFP) mouse for recombination in epithelial cells with motile cilia. Genesis. 2014 Apr;52(4):350-8
• All: 17 reference(s)