Rhbdf2^M2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rhbdf2^M2Btlr
• Name: rhomboid 5 homolog 2; mutation 2, Bruce Beutler
• MGI ID: MGI:5583871
• Synonyms: LosTNF
• Gene: Rhbdf2 Location: Chr11:116488991-116517786 bp, - strand Genetic Position: Chr11, Syntenic
• Alliance: Rhbdf2^M2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion at base pair 116,600,161 (v38) on chromosome 11, or base pair 26,859 in the GenBank genomic region NC_000077. The mutation corresponds to residue 2,485 in the mRNA sequence NM_172572 within exon 18 of 19 total exons. The mutation results in a leucine (L) to glutamine (Q) substitution at position 655 (L655Q). (J:213194)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rhbdf2 Mutation: 84 strains or lines available

References

• Original: J:213194 Zhang Z, et al., Mutagenetix entry for LosTNF. MGI Direct Data Submission. 2014
• All: 1 reference(s)