All Phenotypes Rhbdf2<M2Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rhbdf2^M2Btlr
mutation 2, Bruce Beutler
MGI:5583871

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Rhbdf2^M2Btlr/Rhbdf2⁺	C57BL/6J-Rhbdf2^M2Btlr	MGI:5583875

Allelic Composition	Rhbdf2^M2Btlr/Rhbdf2⁺
Genetic Background	C57BL/6J-Rhbdf2^M2Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf2^M2Btlr mutation (1 available); any Rhbdf2 mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal immune system physiology ( J:213194 )

• some mice exhibited decreased TNFalpha secretion in response to the Toll-like receptor (TLR) ligands LPS (TLR4), Pam3CSK4 (TLR1/2) and R848 (TLR7/8)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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